Pomegranate peel extract alters the microbiome in mice and dysbiosis caused by Citrobacter rodentium infection
نویسندگان
چکیده
منابع مشابه
Amelioration of the effects of Citrobacter rodentium infection in mice by pretreatment with probiotics.
BACKGROUND Citrobacter rodentium is a naturally occurring murine pathogen that causes colonic epithelial-cell hyperplasia, disrupts the colonic mucosa, and elicits a predominantly T helper 1 cellular immune response; it thereby serves as a model for the study of mechanisms of disease induced by human attaching-effacing pathogens. We sought to determine whether pretreatment of mice with a mixtur...
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Citrobacter rodentium is an enteric bacterial pathogen of the mouse intestinal tract that triggers inflammatory responses resembling those of humans infected with enteropathogenic and enterohemorrhagic Escherichia coli. Inflammasome signaling is emerging as a central regulator of inflammatory and host responses to several pathogens, but the in vivo role of inflammasome signaling in host defense...
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The incidence of Trichomonas tenax (T. tenax) in patients with acute ulcerative gingivitis has been demonstrated in several published reports. Metronidazole was known as the most effective drug for human trichomoniasis, however, drug resistance and toxicity appeared. This study was designed in vitro to investigate the inhibitory activity of Punica granatum (P. granatun) ethanol extract on the g...
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Enteropathogenic Escherichia coli, enterohemorrhagic E. coli, and Citrobacter rodentium are classified as attaching and effacing pathogens based on their ability to adhere to the intestinal epithelium via actin-filled membranous protrusions (pedestals). Infection of mice with C. rodentium causes a breach of the intestinal epithelial barrier, leading to colitis via a vigorous inflammatory respon...
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ژورنال
عنوان ژورنال: Food Science & Nutrition
سال: 2019
ISSN: 2048-7177,2048-7177
DOI: 10.1002/fsn3.1106